A 46 year old woman underwent ultrasound guided core biopsy because of a breast mass.
Diagnosis: Benign perineurial adenosis
Discussion: The mass in this case was a radial scar (not shown), and also areas of adenosis, including adenosis in a perineural location.
In some organs, the presence of glands in a perineural location is evidence of neoplasia, but as this case illustrates, perineural glands may be seen in benign conditions of the breast. The presence of glands next to a nerve is a purely incidental finding. The reference given below describes this phenomenon, however using the term ‘invasion’ for a benign condition can be misleading and should be avoided.
Reference: Taylor HB, Norris HJ.
Epithelial invasion of nerves in benign diseases of the breast. Cancer 1967; 20:2245-9.